Science: Chemistry: Organic: Research Groups: S

C-H Bond functionalization in complex organic synthesis, chemical probes for covalent protein modification and imaging of metabolic/signaling pathways.

Synthesis of enzyme inhibitors as potential drug candidates. Reactivity and stability of organolithium compounds. Development of software for NMR data processing and simulation.

Photochemistry. Kinetics and mechanisms of organic reactions.

Synthesis of natural products and small molecules to study biological processes, Transcriptional and translational control of protein synthesis, Molecular control of cellular signaling processes.

Discovery of new reaction methodology and bioorganic chemistry.

Interactions of oligosaccharides with proteins that control cell growth, cell differentiation, cell-cell interactions, bacterial attachment to target cells and signaling events involving the extracellular matrix.

Useful new reactivity and general methods for selectively controlling chemical reactions.

Molecular encapsulation, self-assembling structures, de novo design of proteins organized by organic macrocycles.

Development of new catalytic asymmetric reactions. Synthesis of biologically significant molecules.

New synthetic methodology, asymmetric synthesis, natural product synthesis, and new materials.

Asymmetric catalysis, organic synthesis and organometallic chemistry.

Natural product synthesis, bioorganic chemistry and materials science.

Development of new reactions.

Syntheses of architecturally unique natural products and protein reactive natural products.

Synthesis of biologicaly active and structurally complex natural products and the development of new reaction methodology.

Development of novel coinage metal catalysts. Investigation of the mechanisms of transition metal catalyzed reactions by DFT model calculations.